Executive producer Brad Kern stated Kaley's character was initially brought in as a possible spin-off.
In 2004, Cuoco co-starred in the movie The Hollow with stars Nick Carter and Kevin Zegers.
Her projects include providing the voice of Harley Quinn and playing a stewardess in "The Flight Attendant". Koothrappali ‧ Stephanie Barnett ‧ Lucy ‧ Mary Cooper ‧ Zack Johnson ‧ Beverly Hofstadter ‧ Mike Rostenkowski ‧ Alex Jensen ‧ Professor Proton ‧ Missy Cooper ‧ Ramona Nowitzki ‧ Dan ‧ Josh Wolowitz ‧ Dennis Kim ‧ Althea Davis ‧ Jeanie ‧ Cinnamon ‧ Mrs.
Her TBBT cast-mate Melissa Raunch has also performed the voice of Harley Quinn of the Batman franchise. Rostenkowski ‧ Wyatt ‧ Claire ‧ Kurt ‧ Eric Gablehauser ‧ Dave Gibbs ‧ Dimitri ‧ Alfred Hofstadter ‧ Meemaw ‧ Jimmy Speckerman ‧ Susan ‧ Randall ‧ Bert Kibbler ‧ President Siebert ‧ Janine Davis ‧ Colonel Richard Williams ‧ Halley Wolowitz ‧ Neil Michael Wolowitz ‧ Denise ‧ George Cooper Jr.
Following in the steps of Mayim, Kaley visited Leslie Winkle aka Sara Gilbert on "The Talk" panel show on September 22, 2014.
Kaley Cuoco married her fiancee Karl Cook on June 30, 2018.
Whiskers, Billie Jenkins on the supernatural drama series Charmed, and recently as Penny on the CBS sitcom The Big Bang Theory. Before this, she was known and credited as Kaley Cuoco; and from then on, she begins to be credited as Kaley Cuoco-Sweeting.
After the announcement of their divorce, her credit reverted back to her maiden name as of "The Bachelor Party Corrosion" and was not changed again when she married the next time.
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Her TV hubby and friend Johnny Galecki was in attendance.